
Melanotan II 10mg
Melanotan II
CAS: 121062-08-6
Melanotan II is a cyclic lactam analog of alpha-MSH that potently agonizes MC1R, MC3R, MC4R, and MC5R. MC1R stimulation drives melanogenesis; MC4R activation produces CNS appetite and libido effects. Widely researched for tanning and sexual function. 99.0% HPLC purity.
Specifications
For laboratory research use only. Not for human consumption.
Mechanism of Action
Pan-melanocortin receptor agonism. MC1R in melanocytes stimulates melanin synthesis via cAMP/PKA/MITF pathway, shifting toward eumelanin (dark pigment). MC4R in the hypothalamus modulates appetite and sexual arousal pathways.
Research FAQ
How does Melanotan II differ from Melanotan I?
Melanotan II is a cyclic 7-residue analog that is more potent and activates a broader range of MC receptors (MC1-5R) including CNS MC4R. Melanotan I is a linear 13-residue analog with higher MC1R selectivity.



