MOTS-c 10mg
MOTS-c
CAS: 1627580-76-6
MOTS-c is a mitochondria-derived peptide (MDP) encoded within the 12S rRNA gene of mitochondrial DNA. Activates AMPK signaling to enhance metabolic flexibility and exercise performance. Plasma levels decline with age. 98.8% HPLC purity.
Specifications
For laboratory research use only. Not for human consumption.
Mechanism of Action
AMPK activation via AICAR pathway upregulation in skeletal muscle, promoting fatty acid oxidation, glucose uptake, and mitochondrial biogenesis. Acts as a retrograde signal from mitochondria to the nucleus.
Research FAQ
What makes MOTS-c unique among peptides?
MOTS-c is encoded in mitochondrial DNA rather than nuclear DNA, making it one of the few known mitochondria-derived peptides. It serves as a direct mitochondrial-to-nuclear communication signal involved in cellular energy homeostasis.
Related Compounds
Nicotinamide Adenine Dinucleotide (oxidized)
NAD+ 500mg
L-Alanyl-L-glutamyl-L-aspartyl-glycine
Epithalon 50mg
Water for Injection, 0.9% Benzyl Alcohol