SLU-PP-332 100mg x30 Capsules
SLU-PP-332
CAS: 2413942-14-8
SLU-PP-332 is a first-in-class pan-ERR (estrogen-related receptor) agonist that activates ERRa, ERRb, and ERRg — the master transcriptional regulators of mitochondrial biogenesis and oxidative metabolism. Animal studies show endurance enhancement, fat oxidation, and cardiac protection without exercise. 99.0% HPLC purity.
Specifications
For laboratory research use only. Not for human consumption.
Mechanism of Action
Pan-ERR agonism drives PGC-1a coactivation, upregulating mitochondrial biogenesis genes, fatty acid oxidation enzymes, and oxidative phosphorylation complexes. Unlike AICAR (AMPK-mediated), SLU-PP-332 acts directly on ERR nuclear receptors, producing a transcriptional exercise-adaptation signature.
Research FAQ
How does SLU-PP-332 differ from AICAR?
AICAR activates AMPK indirectly via ZMP. SLU-PP-332 directly agonizes ERR nuclear receptors, producing a broader transcriptional exercise-adaptation response including cardiac and skeletal muscle mitochondrial biogenesis with stronger ERRg activity.
