O-304 (ATX-304) 100mg x60 Capsules
O-304
CAS: N/A
O-304 (ATX-304) is a pan-AMPK activator designed to maintain AMPK in its active state across multiple tissues. Unlike metformin or AICAR, O-304 directly activates AMPK without upstream energy sensing. Phase 2a clinical data in T2D. 99.0% HPLC purity.
Specifications
For laboratory research use only. Not for human consumption.
Mechanism of Action
Binds the AMPK beta subunit carbohydrate-binding module to lock AMPK in an active conformation regardless of cellular energy state. Activates AMPK in fat, muscle, liver, and heart simultaneously.
Research FAQ
How does O-304 differ from AICAR?
AICAR activates AMPK via ZMP mimicry of AMP sensing — context-dependent. O-304 directly locks AMPK in its active conformation regardless of energy status, producing constitutive pan-tissue AMPK activation with superior metabolic effects in clinical data.
